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1. (WO2018182535) SYSTEM FOR OPTICAL MEASUREMENTS AND OPERATION METHOD

Pub. No.:    WO/2018/182535    International Application No.:    PCT/SG2018/050164
Publication Date: Fri Oct 05 01:59:59 CEST 2018 International Filing Date: Fri Mar 30 01:59:59 CEST 2018
IPC: A61B 5/00
G01J 3/10
G01N 21/63
Applicants: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventors: UNNIMADHAVA KURUP SOUDAMINI AMMA, Dinish
BI, Renzhe
FU, Chit Yaw
OLIVO, Malini
Title: SYSTEM FOR OPTICAL MEASUREMENTS AND OPERATION METHOD
Abstract:
A system for optical measurements is provided, comprising: a probe configured to illuminate and to receive a detection light from a sample; a plurality of light sources; a plurality of detectors, optically coupled to the probe and configured to receive the detection light. In a first mode, a first light source is configured to emit a first coherent light, and a first detector is configured to detect a laser speckle signal. In a second mode, a second light source is configured to emit a second coherent light, and a second detector is configured to detect a signal different from the laser speckle signal, for example diffuse reflectance spectroscopy (DRS) or Raman. A third mode may also be provided. A method is also provided, comprising selecting the first mode and carrying out a diffuse speckle contrast analysis (DSCA) measurement of the laser speckle signal, and selecting a different mode from the first mode and carrying out a second measurement.