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1. (WO2018182462) METHOD FOR ENDOTHELIALIZING VASCULAR PROSTHESES

Pub. No.:    WO/2018/182462    International Application No.:    PCT/RU2018/050034
Publication Date: Fri Oct 05 01:59:59 CEST 2018 International Filing Date: Sat Mar 31 01:59:59 CEST 2018
IPC: A61F 2/06
A61L 27/04
A61L 31/08
A61L 33/02
Applicants: AKTSIONERNOE OBSCHESTVO "MEDTEKHNOPROEKT"
АКЦИОНЕРНОЕ ОБЩЕСТВО «МЕДТЕХНОПРОЕКТ»
Inventors: SEDELNIKOV, Nikolai Georgievich
СЕДЕЛЬНИКОВ, Николай Георгиевич
BEKBAEV, Almaz Serikovich
БЕКБАЕВ, Алмаз Серикович
ROMANOVA, Irina Viktorovna
РОМАНОВА, Ирина Викторовна
Title: METHOD FOR ENDOTHELIALIZING VASCULAR PROSTHESES
Abstract:
The invention relates to a method for creating a coating on medical implantable devices placed inside a recipient's body and having at least one surface in contact with blood, in particular on vascular prostheses made of a polymer material (polyethylene terephthalate), with the aim of promoting the endothelialization process and preventing thrombus formation. For this purpose, the indicated method is characterized by alternating steps of ion etching and spraying the coating. The proposed method makes it possible to create a discontinuous coating on a polymeric vascular prosthesis made of polyethylene terephthalate, which is characterized by low thrombogenicity.