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1. (WO2018182346) COMPOSITION FOR DIAGNOSING OR PREDICTING DRUG-INDUCED LONG QT SYNDROME, KIT, AND METHOD FOR DIAGNOSING OR PREDICTING DRUG-INDUCED LONG QT SYNDROME USING SAME
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Pub. No.: WO/2018/182346 International Application No.: PCT/KR2018/003752
Publication Date: 04.10.2018 International Filing Date: 30.03.2018
IPC:
C12Q 1/6883 (2018.01) ,G01N 33/483 (2006.01)
[IPC code unknown for C12Q 1/6883]
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
483
Physical analysis of biological material
Applicants:
고려대학교 산학협력단 KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION [KR/KR]; 서울시 성북구 안암로 145, 고려대학교 (안암동5가) (Anam-dong 5-ga) Korea Univ 145, Anam-ro, Seongbuk-gu Seoul 02841, KR
Inventors:
최종일 CHOI, Jong Il; KR
Agent:
특허법인 무한 MUHANN PATENT & LAW FIRM; 서울시 강남구 언주로 560, 8층 (역삼동, 진영빌딩) (Jinyoung Building, Yeoksam-dong) 8th Floor, 560, Eonju-ro, Gangnam-gu Seoul 06144, KR
Priority Data:
10-2017-004090830.03.2017KR
10-2018-003083416.03.2018KR
Title (EN) COMPOSITION FOR DIAGNOSING OR PREDICTING DRUG-INDUCED LONG QT SYNDROME, KIT, AND METHOD FOR DIAGNOSING OR PREDICTING DRUG-INDUCED LONG QT SYNDROME USING SAME
(FR) COMPOSITION DE DIAGNOSTIC OU DE PRÉDICTION DU SYNDROME DU QT LONG INDUIT PAR UN MÉDICAMENT, KIT, ET PROCÉDÉ DE DIAGNOSTIC OU DE PRÉDICTION DE SYNDROME DU QT LONG INDUIT PAR UN MÉDICAMENT L’UTILISANT
(KO) 약물 유발 QT 연장 증후군 진단 또는 예측용 조성물, 키트 및 이를 이용한 약물 유발 QT 연장 증후군 진단 또는 예측 방법
Abstract:
(EN) The present invention pertains to: a composition by which drug-induced long QT syndrome (diLQTS) can be diagnosed or predicted through E409Q, which is a novel SNTA1 mutation with respect to arrhythmia, more particularly to arrhythmia occurring in drug-induced long QT syndrome patients; a kit; and a diagnosis/prediction method.
(FR) La présente invention concerne : une composition grâce à laquelle le syndrome du QT long induit par un médicament (diLQTS) peut être diagnostiqué ou prédit par E409Q, qui est une nouvelle mutation SNTA1 par rapport à l’arrhythmie, plus particulièrement l’arrhythmie survenant chez les patients présentant un syndrome du QT long induit par un médicament ; un kit ; et un procédé de diagnostic/prédiction.
(KO) 본 발명은 부정맥, 보다 구체적으로는 약물 유발 QT 연장 증후군(drug-induced Long QT Syndrome, diLQTS) 환자에서 발병하는 부정맥에 대한 신규한 SNTA1 돌연변이인 E409Q 를 통해 약물 유발 QT 연장 증후군을 진단 또는 예측할 수 있는 조성물, 키트 및 진단/예측 방법에 관한 것이다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)