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1. (WO2018181207) CHIMERIC ANTIGEN RECEPTOR
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/181207 International Application No.: PCT/JP2018/012194
Publication Date: 04.10.2018 International Filing Date: 26.03.2018
IPC:
C07K 19/00 (2006.01) ,A61K 35/17 (2015.01) ,A61P 35/00 (2006.01) ,C07K 16/18 (2006.01) ,C12N 5/10 (2006.01) ,C12N 15/62 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
19
Hybrid peptides
[IPC code unknown for A61K 35/17]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
10
Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
62
DNA sequences coding for fusion proteins
Applicants:
ノイルイミューン・バイオテック株式会社 NOILE-IMMUNE BIOTECH, INC. [JP/JP]; 東京都中央区銀座7丁目17-2 7-17-2, Ginza, Chuo-ku, Tokyo 1040061, JP
Inventors:
玉田 耕治 TAMADA Koji; JP
佐古田 幸美 SAKODA Yukimi; JP
石▲崎▼ 秀信 ISHIZAKI Hidenobu; JP
Agent:
棚井 澄雄 TANAI Sumio; JP
飯田 雅人 IIDA Masato; JP
服部 映美 HATTORI Emi; JP
Priority Data:
2017-06146127.03.2017JP
Title (EN) CHIMERIC ANTIGEN RECEPTOR
(FR) RÉCEPTEUR ANTIGÉNIQUE CHIMÉRIQUE
(JA) キメラ抗原受容体
Abstract:
(EN) A chimeric antigen receptor containing a target antigen binding domain, a transmembrane domain and a T cell activation signal transduction domain, wherein the target antigen is ganglioside GM2.
(FR) La présente invention concerne un récepteur antigénique chimérique contenant un domaine de liaison à l'antigène cible, un domaine transmembranaire et un domaine de transduction du signal d'activation des cellules T, l'antigène cible étant le ganglioside GM2.
(JA) 標的抗原結合領域と、膜貫通領域と、T細胞活性化シグナル伝達領域とを含み、前記標的抗原がガングリオシドGM2である、キメラ抗原受容体。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)