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1. (WO2018178963) COMPOSITIONS COMPRISING BIODEGRADABLE COPOLYMERS

Pub. No.:    WO/2018/178963    International Application No.:    PCT/IL2017/050389
Publication Date: Fri Oct 05 01:59:59 CEST 2018 International Filing Date: Thu Mar 30 01:59:59 CEST 2017
IPC: A61K 47/34
A61K 9/00
A61K 47/30
C08G 63/06
Applicants: DEXCEL PHARMA TECHNOLOGIES LTD.
Inventors: DOMB, Abraham, J.
GRISHKO, Michael
HANUKA, Ezra
SCHLINGER, Ron
HAGIGIT, Tal
Title: COMPOSITIONS COMPRISING BIODEGRADABLE COPOLYMERS
Abstract:
A depot system containing at least one antibiotic and a biodegradable poly(ester-anhydride) is provided. The system provides prolonged local release of the antibiotic at the site of injection while maintaining the systemic antibiotic levels at sub-therapeutic concentrations.