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1. (WO2018178950) COMPOSITIONS AND METHODS FOR TREATING SYNUCLEINOPATHIES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/178950 International Application No.: PCT/IB2018/052236
Publication Date: 04.10.2018 International Filing Date: 30.03.2018
IPC:
C07K 16/18 (2006.01) ,A61K 39/395 (2006.01) ,A61P 25/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
Applicants: BIOGEN INTERNATIONAL NEUROSCIENCE GMBH[CH/CH]; Landis + Gyr-Strasse 3 6300 Zug, CH
Inventors: PENNER, Natasha; US
MURALIDHARAN, Kumar Kandadi; US
Agent: CONROY, John, F.; Fish & Richardson P.C. Highlight Business Towers Mies-van-der-Rohe-Strasse 8 D-80807 München, DE
Priority Data:
62/479,81831.03.2017US
62/528,79005.07.2017US
Title (EN) COMPOSITIONS AND METHODS FOR TREATING SYNUCLEINOPATHIES
(FR) COMPOSITIONS ET MÉTHODES DE TRAITEMENT DE SYNUCLÉINOPATHIES
Abstract:
(EN) Dosage regimens of anti-α-synuclein antibodies are provided. These dosage regimens find use in the treatment of synucleinopathies such as Parkinson's disease (PD), Parkinson's Disease Dementia (PDD), dementia with Lewy bodies (DLB), Lewy body variant of Alzheimer's disease (LBVAD), pure autonomic failure (PAF), multiple system atrophy (MSA), and neurodegeneration with brain iron accumulation type-1 (NBIA-I).
(FR) L'invention concerne des schémas posologiques d'anticorps anti-α-synucléine. Ces schémas posologiques trouvent une utilisation dans le traitement de synucléinopathies telles que la maladie de Parkinson (PD), la démence de la maladie de Parkinson (PDD), la démence à corps de Lewy (DLB), une variante à corps de Lewy de la maladie d'Alzheimer (LBVAD), une défaillance autonome pure (PAF), l'atrophie multisystème (MSA), et une neurodégénérescence à accumulation de fer cérébrale de type 1 (NBIA-I).
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)