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1. (WO2018178721) METHOD FOR PRODUCING A LIQUID COMPOSITION
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Pub. No.: WO/2018/178721 International Application No.: PCT/GB2018/050887
Publication Date: 04.10.2018 International Filing Date: 29.03.2018
IPC:
A61K 9/00 (2006.01) ,A61K 47/14 (2017.01) ,A61K 9/08 (2006.01) ,A61K 47/44 (2017.01) ,A61K 9/14 (2006.01) ,A61K 9/19 (2006.01) ,A61K 9/48 (2006.01) ,A61K 31/675 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
14
Esters of carboxylic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
08
Solutions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
44
Oils, fats or waxes according to more than one of groups A61K47/02-A61K47/42109
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
19
lyophilised
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
66
Phosphorus compounds
675
having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
Applicants:
THE UNIVERSITY OF LIVERPOOL [GB/GB]; The Foundation Building 765 Brownlow Hill Liverpool Merseyside L69 7ZX, GB
THE JOHNS HOPKINS UNIVERSITY [US/US]; 3400 N. Charles Street Baltimore Maryland 21218, US
Inventors:
RANNARD, Steven Paul; GB
OWEN, Andrew; GB
CURLEY, Paul; GB
HOBSON, James; GB
SICCARDI, Marco; GB
FREEL MEYERS, Caren L.; US
AL-KHOUJA, Amer; US
MEYERS, David J.; US
FLEXNER, Charles Williams; US
Agent:
MARKS & CLERK LLP; 1 New York Street Manchester Greater Manchester M1 4HD, GB
Priority Data:
1705087.330.03.2017GB
Title (EN) METHOD FOR PRODUCING A LIQUID COMPOSITION
(FR) PROCÉDÉ DE PRODUCTION D’UNE COMPOSITION LIQUIDE
Abstract:
(EN) A first aspect of the present invention provides a method of producing a liquid composition comprising stabilised particles of active species in oil by precipitating a solution of the active species in a non-solvent in the presence of one or more stabilisers, mixing the precipitate suspension with an oil and then removing the solvents. Further aspects of the present invention relate to liquid compositions produced by said method and methods of use of such liquid compositions.
(FR) Un premier aspect de la présente invention concerne un procédé de production d’une composition liquide comprenant des particules stabilisées d’espèces actives dans de l’huile par précipitation d’une solution de l’espèce active dans un non-solvant en présence d’un ou plusieurs stabilisants, le mélange de la suspension de précipité avec une huile, puis l’élimination des solvants. D’autres aspects de la présente invention concernent des compositions liquides produites par ledit procédé et des procédés d’utilisation de telles compositions liquides.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)