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1. (WO2018178690) AN AGENT THAT INCREASES THE EXPRESSION OF THE BCL2-ASSOCIATED AGONIST OF CELL DEATH FOR THE TREATMENT OF CANCER

Pub. No.:    WO/2018/178690    International Application No.:    PCT/GB2018/050843
Publication Date: Fri Oct 05 01:59:59 CEST 2018 International Filing Date: Thu Mar 29 01:59:59 CEST 2018
IPC: A61K 45/06
A61K 31/485
A61K 31/555
A61K 31/675
A61K 31/7068
A61P 35/00
G01N 33/50
Applicants: LDN PHARMA LIMITED
Inventors: DALGLEISH, Angus
LUI, Wai
Title: AN AGENT THAT INCREASES THE EXPRESSION OF THE BCL2-ASSOCIATED AGONIST OF CELL DEATH FOR THE TREATMENT OF CANCER
Abstract:
The present invention provides an agent that increases the expression of BAD, for use in the treatment of cancer in conjunction with a chemotherapeutic agent wherein the agent is selected from the list consisting of 6-β-naltrexol, naloxone, methylnaltrexone, or pharmaceutically acceptable salts thereof.