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1. (WO2018178198) BARBITURIC ACID DERIVATIVES COMPRISING CATIONIC AND LIPOPHILIC GROUPS
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Pub. No.: WO/2018/178198 International Application No.: PCT/EP2018/058011
Publication Date: 04.10.2018 International Filing Date: 28.03.2018
IPC:
C07D 233/96 (2006.01) ,A61K 31/515 (2006.01) ,A61P 35/00 (2006.01) ,A61P 31/00 (2006.01)
[IPC code unknown for C07D 233/96][IPC code unknown for A61K 31/515][IPC code unknown for A61P 35][IPC code unknown for A61P 31]
Applicants:
UNIVERSITETET I TROMSØ - NORGES ARKTISKE UNIVERSITET [NO/NO]; PO BOX 6050 Langnes N-9037 Tromsø, NO
Inventors:
STRØM, Morten Bøhmer; NO
BAYER, Annette; NO
ENGQVIST, Stig Olov Magnus; SE
PAULSEN, Marianne Hagensen; NO
AUSBACHER, Dominik; NO
Agent:
DEHNS; St Bride's House 10 Salisbury Square London Greater London EC4Y 8JD, GB
Priority Data:
1705255.631.03.2017GB
Title (EN) BARBITURIC ACID DERIVATIVES COMPRISING CATIONIC AND LIPOPHILIC GROUPS
(FR) DÉRIVÉS D'ACIDE BARBITURIQUE COMPRENANT DES GROUPES CATIONIQUES ET LIPOPHILES
Abstract:
(EN) The present invention relates to bioactive cyclic compounds and their use as antimicrobial agents. In particular, the present invention relates to barbiturate mimics of Eusynstyelamides or small antimicrobial peptides. The compounds of the invention are represented by Formula (I). (I)
(FR) La présente invention concerne des composés cycliques bioactifs et leur utilisation en tant qu'agents antimicrobiens. La présente invention concerne particulièrement des mimétiques barbituriques d'Eusynstyelamides ou de petits peptides antimicrobiens. Les composés de l'invention sont représentés par la formule (I). (I)
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)