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1. (WO2018178126) RECOMBINANT HOST CELL WITH ALTERED MEMBRANE LIPID COMPOSITION
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/178126 International Application No.: PCT/EP2018/057853
Publication Date: 04.10.2018 International Filing Date: 28.03.2018
IPC:
C12N 15/63 (2006.01) ,C12P 21/00 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21
Preparation of peptides or proteins
Applicants: BOEHRINGER INGELHEIM RCV GMBH & CO KG[AT/AT]; Dr.-Boehringer-Gasse 5-11 1121 Wien, AT
SANDOZ AG[CH/CH]; Lichtstrasse 35 4056 Basel, CH
VTU TECHNOLOGY GMBH[AT/AT]; Parkring 18 8074 Grambach, AT
BIOMIN HOLDING GMBH[AT/AT]; Industriestrasse 21 3130 Herzogenburg, AT
LONZA LTD[CH/CH]; Lonzastrasse 3930 Visp, CH
Inventors: GRILLITSCH, Karlheinz; AT
DAUM, Guenther; AT
GRUTSCH, Andreas; AT
Agent: WEINZIERL, Gerhard; DE
KOCH, Andreas Dr.; DE
SCHIWECK, Wolfram Dr.; DE
Priority Data:
17163588.129.03.2017EP
Title (EN) RECOMBINANT HOST CELL WITH ALTERED MEMBRANE LIPID COMPOSITION
(FR) CELLULE HÔTE RECOMBINANTE À COMPOSITION LIPIDIQUE MEMBRANAIRE MODIFIÉE
Abstract:
(EN) The present invention is in the field of recombinant biotechnology, in particular in the field of protein expression. The invention generally relates to a method of expressing a protein of interest (POI) from a host cell. The invention relates particularly to improving a host cell's capacity to express and/or secrete a protein of interest and use of the host cell for protein expression. The invention also relates to cell culture technology, and more specifically to culturing cells to produce desired molecules for medical purposes or food products.
(FR) La présente invention se rapporte au domaine de la biotechnologie recombinante, en particulier au domaine de l'expression de protéines. D'une manière générale, l'invention concerne un procédé d'expression d'une protéine d'intérêt (POI) à partir d'une cellule hôte. L'invention concerne, en particulier, l'amélioration de la capacité d'une cellule hôte à exprimer et/ou sécréter une protéine d'intérêt et à utiliser la cellule hôte pour l'expression de protéines. L'invention concerne également une technologie de culture cellulaire et, de manière plus spécifique, la culture de cellules pour produire des molécules souhaitées à des fins médicales ou pour des produits alimentaires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)