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1. (WO2018178013) MODIFIED MUSSEL PROTEINS, USES THEREOF AND RELATED COMPOUNDS
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Pub. No.: WO/2018/178013 International Application No.: PCT/EP2018/057641
Publication Date: 04.10.2018 International Filing Date: 26.03.2018
IPC:
C07K 14/435 (2006.01) ,C12P 21/00 (2006.01) ,C12N 9/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21
Preparation of peptides or proteins
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
Applicants:
TECHNISCHE UNIVERSITÄT BERLIN [DE/DE]; Straße des 17. Juni 135 10623 Berlin, DE
HUMBOLDT-UNIVERSITÄT ZU BERLIN [DE/DE]; Unter den Linden 6 10099 Berlin, DE
Inventors:
HAUF, Matthias; DE
BUDISA, Nediljko; DE
RICHTER, Florian; DE
BAUMANN, Tobias; DE
SCHNEIDER, Tobias; DE
Agent:
MAIKOWSKI & NINNEMANN PATENTANWÄLTE PARTNERSCHAFT MBB; Kurfürstendamm 54-55 Postfach 15 09 20 10707 Berlin, DE
Priority Data:
17163362.128.03.2017EP
Title (EN) MODIFIED MUSSEL PROTEINS, USES THEREOF AND RELATED COMPOUNDS
(FR) PROTÉINES MODIFIÉES DE MOULE, UTILISATIONS CORRESPONDANTES ET COMPOSÉS APPARENTÉS
Abstract:
(EN) The invention relates to modified mussel adhesive proteins, to uses thereof, to nucleotide sequences encoding the modified mussel adhesive proteins, to an aminoacyl-tRNA synthetase suited for producing the modified mussel adhesive proteins, and to a novel use of a photocaged 3,4-dihydroxyphenylalanine derivative comprising a protecting group that can be cleaved from the 3,4-dihydroxyphenylalanine derivative residue by irradiation with UV light on at least one hydroxyl residue of its catechol moiety, in particular of ortho-nitrobenzyl-3,4-dihydroxyphenylalanine.
(FR) L'invention concerne des protéines adhésives modifiées de moule, leurs utilisations, des séquences nucléotidiques codant pour les protéines adhésives modifiées de moule, une aminoacyl-ARNt synthétase appropriée pour produire les protéines adhésives modifiées de moule et une nouvelle utilisation d'un dérivé de 3,4-dihydroxyphénylalanine photo-cagé comprenant un groupe protecteur qui peut être dissocié à partir du résidu dérivé de 3,4-dihydroxyphénylalanine par irradiation par de la lumière UV sur au moins un résidu hydroxyle de son fragment catéchol, en particulier l'ortho-nitrobenzyl-3,4-dihydroxyphénylalanine.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)