Search International and National Patent Collections

1. (WO2018178013) MODIFIED MUSSEL PROTEINS, USES THEREOF AND RELATED COMPOUNDS

Pub. No.:    WO/2018/178013    International Application No.:    PCT/EP2018/057641
Publication Date: Fri Oct 05 01:59:59 CEST 2018 International Filing Date: Tue Mar 27 01:59:59 CEST 2018
IPC: C07K 14/435
C12P 21/00
C12N 9/00
Applicants: TECHNISCHE UNIVERSITÄT BERLIN
HUMBOLDT-UNIVERSITÄT ZU BERLIN
Inventors: HAUF, Matthias
BUDISA, Nediljko
RICHTER, Florian
BAUMANN, Tobias
SCHNEIDER, Tobias
Title: MODIFIED MUSSEL PROTEINS, USES THEREOF AND RELATED COMPOUNDS
Abstract:
The invention relates to modified mussel adhesive proteins, to uses thereof, to nucleotide sequences encoding the modified mussel adhesive proteins, to an aminoacyl-tRNA synthetase suited for producing the modified mussel adhesive proteins, and to a novel use of a photocaged 3,4-dihydroxyphenylalanine derivative comprising a protecting group that can be cleaved from the 3,4-dihydroxyphenylalanine derivative residue by irradiation with UV light on at least one hydroxyl residue of its catechol moiety, in particular of ortho-nitrobenzyl-3,4-dihydroxyphenylalanine.