WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Options
Query Language
Stem
Sort by:
List Length
Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2018177857) SYMMETRICAL 2-AMINOPHENYL-BENZAZOLYL-5-ACETATE COMPOUNDS AND THEIR USE AS ANTI-HEPARANASE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2018/177857 International Application No.: PCT/EP2018/057239
Publication Date: 04.10.2018 International Filing Date: 22.03.2018
IPC:
C07D 235/18 (2006.01) ,C07D 263/57 (2006.01) ,C07F 5/02 (2006.01) ,A61K 31/423 (2006.01) ,A61P 35/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
235
Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02
condensed with carbocyclic rings or ring systems
04
Benzimidazoles; Hydrogenated benzimidazoles
18
with aryl radicals directly attached in position 2
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
263
Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
52
condensed with carbocyclic rings or ring systems
54
Benzoxazoles; Hydrogenated benzoxazoles
56
with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
57
Aryl or substituted aryl radicals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
F
ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
5
Compounds containing elements of the 3rd Group of the Periodic System
02
Boron compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
42
Oxazoles
423
condensed with carbocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants: LEADIANT BIOSCIENCES SA IN LIQUIDAZIONE[CH/CH]; Corso Elvezia 9 6900 Lugano, CH
Inventors: GIANNINI, Giuseppe; IT
BATTISTUZZI, Gianfranco; IT
DI SANTO, Roberto; IT
COSTI, Roberta; IT
MESSORE, Antonella; IT
Agent: GHIRARDI, Valeria; IT
SPADARO, Marco; IT
CANTALUPPI, Stefano; IT
LOCAS, Davide; IT
FABRIS, Stefano; IT
SUSANETTO, Carlo; IT
MORABITO, Sara; IT
LEONE, Mario; IT
CURRADO, Luisa; IT
Priority Data:
17163014.827.03.2017EP
Title (EN) SYMMETRICAL 2-AMINOPHENYL-BENZAZOLYL-5-ACETATE COMPOUNDS AND THEIR USE AS ANTI-HEPARANASE
(FR) COMPOSÉS SYMÉTRIQUES DE 2-AMINOPHÉNYL-BENZAZOLYL-5-ACÉTATE ET LEUR UTILISATION COMME ANTI-HÉPARANASE
Abstract:
(EN) The present invention relates to symmetrical 2-aminophenyl-benzazolyl-5-acetate compoundsof formula (I). Such compounds are endowed with an anti-heparanase activity. The present invention also relates to the use of such compounds as a medicament, in particular for the treatment of diseases and disorders associated with a heparanase activity, and to pharmaceutical compositions comprising the same.
(FR) La présente invention concerne des composés symétriques de 2-aminophényl-benzazolyl-5-acétate de formule (I). Selon l'invention, lesdits composés sont dotés d'une activité anti-héparanase. La présente invention concerne également l'utilisation de tels composés en tant que médicament, en particulier pour le traitement de maladies et de troubles associés à une activité d'héparanase, et des compositions pharmaceutiques les comprenant.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)