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1. (WO2018177376) VIRAL VECTOR FOR TREATING AUTOIMMUNE DISEASE AND DIABETES AND CONSTRUCTION METHOD AND APPLICATION THEREOF

Pub. No.:    WO/2018/177376    International Application No.:    PCT/CN2018/081117
Publication Date: Fri Oct 05 01:59:59 CEST 2018 International Filing Date: Fri Mar 30 01:59:59 CEST 2018
IPC: C12N 15/867
C12N 15/864
C12N 15/66
C12N 7/04
A61K 48/00
A61K 9/00
A61P 3/10
A61P 37/02
A61P 29/00
A61P 19/02
Applicants: GUANGZHOU HUAZHEN PHARMACEUTICAL CO., LTD
广州华真医药科技有限公司
Inventors: ZHAO, Allan Zijian
赵子建
BI, Xinyun
毕欣耘
LI, Xiaoxi
李晓曦
LI, Fanghong
李芳红
LIN, Yan
林艳
Title: VIRAL VECTOR FOR TREATING AUTOIMMUNE DISEASE AND DIABETES AND CONSTRUCTION METHOD AND APPLICATION THEREOF
Abstract:
Provided are a viral vector for treating an autoimmune disease and diabetes and a construction method and an application thereof. The viral vector is a lentiviral expression plasmid or an adeno-associated viral expression plasmid cloned with mfat-1 gene, and the mfat-1 gene is as shown in SEQ ID No.: 1.