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1. (WO2018177140) USE OF LIPOSOME FOR TREATMENT OF CHRONIC VIRAL HEPATITIS B

Pub. No.:    WO/2018/177140    International Application No.:    PCT/CN2018/079266
Publication Date: Fri Oct 05 01:59:59 CEST 2018 International Filing Date: Sat Mar 17 00:59:59 CET 2018
IPC: A61K 9/127
A61K 9/19
A61K 47/42
A61K 47/32
A61P 1/16
A61P 31/20
Applicants: JIANGSU MENDEL GENE TECHNOLOGY CO., LTD
江苏孟德尔基因科技有限公司
Inventors: WU, Yuzhang
吴玉章
Title: USE OF LIPOSOME FOR TREATMENT OF CHRONIC VIRAL HEPATITIS B
Abstract:
Disclosed is the use of a liposome itself for the preparation of a drug for treating chronic viral hepatitis B, wherein the liposome is prepared from a substance comprising a phospholipid and cholesterol. Also disclosed is the use of the liposome itself for preparing drugs for promoting the serological conversion of the hepatitis B E antibody to positive and of the hepatitis B E antigen to negative in patients with chronic viral hepatitis B, for reducing the titer of the hepatitis B virus in the peripheral blood serum of patients with chronic viral hepatitis B, for reducing the glutamic-pyruvic transaminase concentration in the peripheral blood serum of patients with chronic viral hepatitis B, and for maintaining the stability of the T cell receptor library for patients with chronic viral hepatitis B.