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1. (WO2018176844) CAR-CIK TRANSGENIC CELL, PREPARATION METHOD THEREFOR AND USE THEREOF

Pub. No.:    WO/2018/176844    International Application No.:    PCT/CN2017/110659
Publication Date: Fri Oct 05 01:59:59 CEST 2018 International Filing Date: Tue Nov 14 00:59:59 CET 2017
IPC: C12N 5/10
C12N 5/0783
C12N 15/867
A61K 35/17
A61P 35/00
Applicants: SHANGHAI UNICAR-THERAPY BIO-MEDICINE TECHNOLOGY CO., LTD
上海优卡迪生物医药科技有限公司
Inventors: KANG, Liqing
康立清
YU, Zhou
余宙
ZHAO, Shimin
赵世民
YU, Lei
俞磊
QI, Wei
祁伟
Title: CAR-CIK TRANSGENIC CELL, PREPARATION METHOD THEREFOR AND USE THEREOF
Abstract:
Provided is a CAR-CIK transgenic cell containing a chimeric antigen receptor (CAR) gene targeting a CD19 antigen, a CD56 cell and a CD3 cell, wherein the expression of the CAR gene, CD56 cell and CD3 cell is positive. Also provided are a method for preparing the CAR-CIK transgenic cell and the use thereof in the preparation of a drug for treating tumour cells.