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1. (WO2018176098) PROPHYLAXIS AND TREATMENT OF COGNITIVE DYSFUNCTION AND DECLINE
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Pub. No.: WO/2018/176098 International Application No.: PCT/AU2018/050294
Publication Date: 04.10.2018 International Filing Date: 29.03.2018
IPC:
A61K 31/7016 (2006.01) ,A61P 25/28 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7016
Disaccharides, e.g. lactose, lactulose
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
28
for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applicants:
THE FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH [AU/AU]; L 5, Kenneth Myer Building, 30 Royal Parade, The University of Melbourne Parkville, Victoria 3010, AU
Inventors:
ADLARD, Paul; AU
PORTBURY, Stuart; AU
Agent:
DAVIES COLLISON CAVE PTY LTD; 255 Elizabeth Street Sydney, New South Wales 2000, AU
Priority Data:
201790117131.03.2017AU
Title (EN) PROPHYLAXIS AND TREATMENT OF COGNITIVE DYSFUNCTION AND DECLINE
(FR) PROPHYLAXIE ET TRAITEMENT D'UN DYSFONCTIONNEMENT ET D'UN DÉCLIN COGNITIFS
Abstract:
(EN) Provided in accordance with the present disclosure are methods for preventing or reducing cognitive dysfunction or decline associated with an acquired brain injury, for treating cognitive dysfunction or decline associated with an acquired brain injury, and for inducing or increasing neuroplasticity, the methods comprising administering to a subject in need thereof a therapeutically effective amount of trehalose.
(FR) La présente invention concerne des méthodes permettant de prévenir ou de réduire un dysfonctionnement ou un déclin cognitifs associés à une lésion cérébrale acquise, de traiter un dysfonctionnement ou un déclin cognitifs associés à une lésion cérébrale acquise, et d'induire ou d'augmenter la neuroplasticité, les méthodes comprenant l'administration à un sujet qui en a besoin d'une quantité thérapeutiquement efficace de tréhalose.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)