Search International and National Patent Collections
|1. (WO2018176075) CHIMERIC INSECT-SPECIFIC FLAVIVIRUSES|
|Applicants:||THE UNIVERSITY OF QUEENSLAND
|Title:||CHIMERIC INSECT-SPECIFIC FLAVIVIRUSES|
Chimeric proteins that comprise one or more amino acid sequences of an insect- specific flavivirus and one or more other immunogenic proteins are provided. The chimeric proteins are suitably capable of forming virus particles. The chimeric protein and/or virus particle may be suitable for delivery to a subject to elicit an immune response to a pathogen and/or for diagnosis or detection of a pathogen. Also provided are nucleic acids and vectors encoding the chimeric proteins, and isolated chimeric insect-specific flaviviruses comprising the chimeric proteins and/or nucleic acids.