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1. WO2018172491 - A METHOD FOR CHARACTERIZING OPTICAL PROPERTIES OF A NON-LINEAR IMAGING DEVICE USING HARMONIC GENERATION NANOPROBES

Publication Number WO/2018/172491
Publication Date 27.09.2018
International Application No. PCT/EP2018/057375
International Filing Date 22.03.2018
IPC
G02B 21/16 2006.1
GPHYSICS
02OPTICS
BOPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
21Microscopes
16adapted for ultra-violet illumination
G01N 21/64 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
G01Q 40/02 2010.1
GPHYSICS
01MEASURING; TESTING
QSCANNING-PROBE TECHNIQUES OR APPARATUS; APPLICATIONS OF SCANNING-PROBE TECHNIQUES, e.g. SCANNING-PROBE MICROSCOPY
40Calibration, e.g. of probes
02Calibration standards or methods of fabrication thereof
G01N 21/27 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
17Systems in which incident light is modified in accordance with the properties of the material investigated
25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
27using photo-electric detection
G02B 21/34 2006.1
GPHYSICS
02OPTICS
BOPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
21Microscopes
34Microscope slides, e.g. mounting specimens on microscope slides
G02B 21/24 2006.1
GPHYSICS
02OPTICS
BOPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
21Microscopes
24Base structure
CPC
G02B 21/16
GPHYSICS
02OPTICS
BOPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
21Microscopes
16adapted for ultra-violet illumination ; ; Fluorescence microscopes
G02B 21/244
GPHYSICS
02OPTICS
BOPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
21Microscopes
24Base structure
241Devices for focusing
244using image analysis techniques
G02B 21/34
GPHYSICS
02OPTICS
BOPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
21Microscopes
34Microscope slides, e.g. mounting specimens on microscope slides
G02B 21/367
GPHYSICS
02OPTICS
BOPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
21Microscopes
36arranged for photographic purposes or projection purposes
365Control or image processing arrangements for digital or video microscopes
367providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
G02B 27/0025
GPHYSICS
02OPTICS
BOPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
27Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
0025for optical correction, e.g. distorsion, aberration
Applicants
  • ECOLE POLYTECHNIQUE [FR]/[FR]
  • CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE [FR]/[FR]
Inventors
  • GACOIN, Thierry
  • MAHOU, Pierre
  • MALKINSON, Guy
  • SUPATTO, Willy, Jean-Claude
  • BEAUREPAIRE, Emmanuel, Jean-Marc
Agents
  • CABINET NONY
Priority Data
17305323.222.03.2017EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A METHOD FOR CHARACTERIZING OPTICAL PROPERTIES OF A NON-LINEAR IMAGING DEVICE USING HARMONIC GENERATION NANOPROBES
(FR) PROCÉDÉ DE CARACTÉRISATION DES PROPRIÉTÉS OPTIQUES D'UN DISPOSITIF D'IMAGERIE NON LINÉAIRE UTILISANT DES NANOSONDES DE GÉNÉRATION D'HARMONIQUES
Abstract
(EN)
Method for characterizing at least one optical property of any non-linear imaging device, the method comprising: exciting at at least one arbitrary wavelength selected in a range of excitation wavelengths a calibration tool (3) comprising a predefined distribution of harmonic generating nanoparticles (6); acquiring at least one optical signal generated by the calibration tool in response to this excitation; and processing the at least one signal to generate therefrom data useful to characterize said at least one optical property of the device, said at least one optical property being preferably selected among a spatial resolution of the imaging device, a laser beam or optics alignment, a chromatic aberration and a field curvature.
(FR)
L'invention concerne un procédé de caractérisation d'au moins une propriété optique d'un dispositif d'imagerie non linéaire, le procédé consistant : à exciter, à au moins une longueur d'onde arbitraire sélectionnée dans une plage de longueurs d'onde d'excitation, un outil d'étalonnage (3) comprenant une distribution prédéfinie de nanoparticules génératrices d'harmoniques (6) ; à acquérir au moins un signal optique généré par l'outil d'étalonnage en réponse à cette excitation ; et à traiter lesdits signaux pour générer à partir de ces derniers des données utiles pour caractériser ladite au moins une propriété optique du dispositif, ladite propriété optique étant de préférence choisie parmi une résolution spatiale du dispositif d'imagerie, un alignement de faisceau laser ou optique, une aberration chromatique et une courbure de champ.
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