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1. (WO2018167139) SUBCUTANEOUS ADMINISTRATION OF A P2Y12 RECEPTOR ANTAGONIST

Pub. No.:    WO/2018/167139    International Application No.:    PCT/EP2018/056372
Publication Date: Fri Sep 21 01:59:59 CEST 2018 International Filing Date: Thu Mar 15 00:59:59 CET 2018
IPC: A61K 31/506
A61P 7/02
Applicants: IDORSIA PHARMACEUTICALS LTD
Inventors: BAUMANN, Martine
KRAMBERG, Markus
REY, Markus
RIEDERER, Markus
ROUX, Sebastien
Title: SUBCUTANEOUS ADMINISTRATION OF A P2Y12 RECEPTOR ANTAGONIST
Abstract:
The present invention relates to a P2Y12 receptor antagonist selected from the group consisting of4-((R)-2-{[6-((S)-3-methoxy-pyrrolidin-1-yl)-2-phenyl-pyrimidine-4-carbonyl]-amino}-3-phosphono-propionyl)-piperazine-1-carboxylic acid butyl ester, (1S,2S,3R,5S)-3- [7-[(1R,2S)-2-(3,4-difluorophenyl)cyclopropylamino]-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol, and (1S,2R,3S,4R)-4-[7- [(1R,2S)-2-(3,4-difluorophenyl)cyclopropylamino]-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]cyclopentane-1,2,3-triol, or a pharmaceutically acceptable salt thereof, for use as a medicament by subcutaneous or intradermal administration.