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1. (WO2018166546) METHOD FOR THE CHROMATOGRAPHIC QUANTITATIVE DETERMINATION OF THE AMINO ACIDS VALINE, METHIONINE, ALLO-ISOLEUCINE, ISOLEUCINE, LEUCINE, TYROSINE AND PHENYLALANINE IN BLOOD PLASMA
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Pub. No.: WO/2018/166546 International Application No.: PCT/DE2017/000412
Publication Date: 20.09.2018 International Filing Date: 05.12.2017
IPC:
G01N 33/68 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants: MEMBRAPURE GMBH[DE/DE]; Wolfgang-Küntscher-Straße 14 16761 Hennigsdorf, DE
Inventors: FLINDT, Erdmann; DE
TIMMERMANN, Detlef; DE
Agent: PATENTANWALTSKANZLEI DR. HERRGUTH; Burckhardtstraße 1 30163 Hannover, DE
Priority Data:
10 2017 002 523.116.03.2017DE
Title (EN) METHOD FOR THE CHROMATOGRAPHIC QUANTITATIVE DETERMINATION OF THE AMINO ACIDS VALINE, METHIONINE, ALLO-ISOLEUCINE, ISOLEUCINE, LEUCINE, TYROSINE AND PHENYLALANINE IN BLOOD PLASMA
(FR) PROCÉDÉ DE DÉTERMINATION QUANTITATIVE CHROMATOGRAPHIQUE DES ACIDES AMINÉS VALINE, MÉTHIONINE, ALLO-ISOLEUCINE, ISOLEUCINE, LEUCINE, TYROSINE ET PHÉNYLALANINE DANS LE PLASMA SANGUIN
(DE) VERFAHREN ZUR CHROMATOGRAFISCHEN QUANTITATIVEN BESTIMMUNG DER AMINOSÄUREN VALIN, METHIONIN, ALLO-ISOLEUCIN, ISOLEUCIN, LEUCIN, TYROSIN UND PHENYLALANIN IM BLUTPLASMA
Abstract:
(EN) The invention relates in particular to a method for the chromatographic quantitative determination of the amino acids valine, methionine, allo-isoleucine, isoleucine, leucine, tyrosine and phenylalanine in blood plasma, characterized in that the amino acid homocysteine is quantitatively detected at the same time in a single chromatography run.
(FR) La présente invention concerne un procédé de détermination quantitative chromatographique des acides aminés valine, méthionine, allo-isoleucine, isoleucine, leucine, tyrosine et phénylalanine dans le plasma sanguin, caractérisé en ce que l'acide aminé homocystéine est détecté dans le même temps de manière quantitative au cours d'un seul cycle de chromatographie.
(DE) Es wird insbesondere ein Verfahren zur chromatografischen quantitativen Bestimmung von den Aminosäuren Valin, Methionin, allo-Isoleucin, Isoleucin, Leucin, Tyrosin und Phenylalanin im Blutplasma offenbart, dadurch gekennzeichnet, dass die Aminosäure Homocystein in einem einzigen Chromatografielauf quantitativ miterfasst wird.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: German (DE)
Filing Language: German (DE)