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1. (WO2018166468) IGG-LIKE LONG-ACTING IMMUNE FUSION PROTEIN AND USE THEREOF

Pub. No.:    WO/2018/166468    International Application No.:    PCT/CN2018/078951
Publication Date: Fri Sep 21 01:59:59 CEST 2018 International Filing Date: Thu Mar 15 00:59:59 CET 2018
IPC: C07K 19/00
C12N 15/00
A61K 38/00
A61K 38/26
A61P 3/10
A61P 37/00
A61P 35/00
A61P 5/00
Applicants: BEIJING BEYOND BIOTECHNOLOGY CO., LTD.
北京比洋生物技术有限公司
Inventors: HU, PinLiang
胡品良
HE, Yun
何芸
ZOU, Jing
邹敬
HONG, WeiDong
洪伟东
SONG, LingYun
宋凌云
YANG, ZeRong
杨泽荣
Title: IGG-LIKE LONG-ACTING IMMUNE FUSION PROTEIN AND USE THEREOF
Abstract:
Disclosed are an IgG-like long-acting immune fusion protein and the use thereof. The IgG-like long-acting immune fusion protein consists of an effector molecule and a constant region of an IgG antibody, and the effector molecule is linked to the constant region of the IgG antibody by means of a linker peptide; the effector molecule is a protein capable of exerting physiological functions in the body; and the constant region of the IgG antibody is a structure of the IgG antibody with two heavy chain variable regions and two light chain variable regions removed.