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1. (WO2018165649) PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

Pub. No.:    WO/2018/165649    International Application No.:    PCT/US2018/021939
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Tue Mar 13 00:59:59 CET 2018
IPC: A61K 31/444
A61K 31/496
A61K 31/5513
Applicants: EMBERA NEUROTHERAPEUTICS, INC.
Inventors: STRAUB, Julie
DUVVURI, Muralikrishna
VED, Parag, M.
REHLAENDER, Bruce
BREAUX, Jay
VADINO, Winston, A.
BORAH, Kripanath
GLOFF, Carol
Title: PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
Abstract:
Provided are pharmaceutical compositions useful for the treatment and/or prevention of a disorder, such as addiction. For example, pharmaceutical compositions are provided that comprise a first active pharmaceutical component (e.g., metyrapone) and a second active pharmaceutical component (e.g., oxazepam). The compositions may be constructed in such a manner as to limit the physical contact between the first and second active pharmaceutical components, thus preventing any degradation of the active pharmaceutical components resulting form interaction between the two components. The compositions may include at least one pharmaceutically acceptable excipient. Also provided are methods of making the compositions as well as kits containing materials to provide the compositions.