Search International and National Patent Collections

1. (WO2018165594) COMPOSITIONS AND METHODS FOR PRODUCING HIGH SECRETED YIELDS OF RECOMBINANT PROTEINS

Pub. No.:    WO/2018/165594    International Application No.:    PCT/US2018/021817
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Sat Mar 10 00:59:59 CET 2018
IPC: C07K 14/00
C07K 14/435
C40B 40/02
Applicants: BOLT THREADS, INC.
Inventors: KITTLESON, Joshua
STEVENS, Thomas
HILL, Rena
PESCE, Carlos Gustavo
Title: COMPOSITIONS AND METHODS FOR PRODUCING HIGH SECRETED YIELDS OF RECOMBINANT PROTEINS
Abstract:
The present disclosure relates to methods for producing recombinant proteins, as well as compositions used in and produced by such methods. Specifically, the present disclosure relates to methods for producing high secreted yields of recombinant proteins, and the compositions provided herein include recombinant host cells that comprise polynucleotide sequences encoding proteins operably linked to at least 2 distinct secretion signals.