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1. (WO2018165198) CELL-BASED METHODS AND COMPOSITIONS FOR THERAPEUTIC AGENT DELIVERY AND TREATMENTS USING SAME
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Pub. No.: WO/2018/165198 International Application No.: PCT/US2018/021206
Publication Date: 13.09.2018 International Filing Date: 06.03.2018
IPC:
C12N 5/10 (2006.01) ,C12N 15/67 (2006.01) ,A61K 47/50 (2017.01) ,C07K 16/28 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
10
Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
67
General methods for enhancing the expression
[IPC code unknown for A61K 47/50]
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
Applicants:
UNIVERSITY OF WASHINGTON [US/US]; 4545 Roosevelt Way NE Suite 400 Seattle, Washington 98105, US
SEATTLE CHILDREN'S RESEARCH INSTITUTE [US/US]; 4800 Sand Point Way NE Seattle, Washington 98105, US
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION [AU/AU]; Clunies Ross Street Acton, Australian Capital Territory 2601, AU
Inventors:
STAYTON, Patrick, S.; US
CONVERTINE, Anthony; US
DAS, Debobrato; US
SON, Hye-Nam; US
SRINIVASAN, Selvi; US
MONTGOMERY, Katherine; US
BLUMENTHAL, Ian; US
CRANE, Courtney; US
JENSEN, Michael; US
MATTHAEI, James; US
CHIEFARI, John; AU
DANIAL, Maarten; AU
HUANG, Fei; AU
MACDONALD, James; AU
POSTMA, Almar; AU
TURNER, Kathleen; AU
Agent:
FITZGERALD, Mark, J.; US
RESNICK, David S.; US
EISENSTEIN, Ronald I.; US
BENN, Susanna C.; US
BRAICH, Ravinderjit S.; US
CROSBY, David F.; US
HUFF, Shayne Y.; US
MILLS, Tari W.; US
PTASHKA, Teresa A.; US
SUMMERFORD, Candace M.; US
KLING, Nicole D.; US
Priority Data:
62/467,66306.03.2017US
Title (EN) CELL-BASED METHODS AND COMPOSITIONS FOR THERAPEUTIC AGENT DELIVERY AND TREATMENTS USING SAME
(FR) MÉTHODES ET COMPOSITIONS À BASE DE CELLULES DESTINÉES À L'ADMINISTRATION D'AGENTS THÉRAPEUTIQUES ET TRAITEMENTS LES UTILISANT
Abstract:
(EN) Provided herein are engineered cells and methods for engineering cells to deliver a therapeutic agent, e.g., a small molecule, peptide or other drug, to a cell or tissue to be treated.
(FR) L'invention concerne des cellules modifiées et des procédés de modification de cellules destinés à administrer un agent thérapeutique, par exemple une petite molécule, un peptide ou un autre médicament, à une cellule ou un tissu à traiter.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)