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1. (WO2018165077) BIORESORBABLE EXOPOLYSACCHARIDES

Pub. No.:    WO/2018/165077    International Application No.:    PCT/US2018/021022
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Wed Mar 07 00:59:59 CET 2018
IPC: C07K 14/32
C12N 9/12
C12N 9/90
C12N 9/10
C07K 14/245
Applicants: DEPUY SYNTHES PRODUCTS, INC.
Inventors: BUECHTER, Douglas D.
Title: BIORESORBABLE EXOPOLYSACCHARIDES
Abstract:
The present disclosure is directed to microorganisms that are genetically modified to express at least one exogenous enzyme involved in N-acetylglucosamine uptake and metabolism. Methods for the production of an exopolysaccharide are also disclosed. The exopolysaccharide comprises N-acetylglucosamine and D-glucose and may be used as a bioresorbable implant for soft tissue repair, replacement, or augmentation.