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1. (WO2018164573) VIRAL POLYPEPTIDE INHIBITORS
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2018/164573 International Application No.: PCT/NL2018/050137
Publication Date: 13.09.2018 International Filing Date: 06.03.2018
IPC:
A61K 38/55 (2006.01) ,A61P 31/14 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
55
Protease inhibitors
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12
Antivirals
14
for RNA viruses
Applicants:
ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC [NL/NL]; Albinusdreef 2 2333 ZA Leiden, NL
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO [CA/CA]; 27 King's College Circle Toronto, Ontario M5S 1A1, CA
UNIVERSITY OF MANITOBA [CA/CA]; 207 Administration Building Winnipeg, Manitoba R3T 2N2, CA
Inventors:
KIKKERT, Marjolein; NL
KNAAP, Robert Cornells Martinus; NL
SIDHU, Sachdev Singh; CA
ZHANG, Wei; CA
MARK, Brian Leonard; CA
BAILEY-ELKIN, Ben Allan; CA
Agent:
JANSEN, CM.; V.O. Carnegieplein 5 2517 KJ Den Haag, NL
Priority Data:
17159420.306.03.2017EP
Title (EN) VIRAL POLYPEPTIDE INHIBITORS
(FR) INHIBITEURS DE POLYPEPTIDES VIRAUX
Abstract:
(EN) The disclosure provides polypeptide inhibitors of viral proteins, useful in the treatment and prevention of viral infection. The viral inhibitors are particularly useful for treating Middle East respiratory syndrome coronaviral (MERS-CoV) infection, Crimean-Congo hemorrhagic fever viral infection, or the symptoms of infection.
(FR) L'invention concerne des inhibiteurs polypeptidiques de protéines virales, utiles dans le traitement et la prévention d'une infection virale. Les inhibiteurs viraux sont particulièrement utiles pour traiter une infection par le coronavirus du syndrome respiratoire du Moyen-Orient (MERS-CoV), une infection virale de la fièvre hémorragique de Crimée-Congo, ou les symptômes d'une infection.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)