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1. (WO2018164507) EXTRACELLULAR MATRIX-PRODUCING COMPOSITION USING MAST4 GENE AND PREPARATION METHOD THEREFOR
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Pub. No.: WO/2018/164507 International Application No.: PCT/KR2018/002763
Publication Date: 13.09.2018 International Filing Date: 08.03.2018
IPC:
C12N 5/077 (2010.01) ,C12N 9/22 (2006.01) ,C12N 15/10 (2006.01) ,C12N 15/90 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
077
Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14
Hydrolases (3.)
16
acting on ester bonds (3.1)
22
Ribonucleases
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
10
Processes for the isolation, preparation or purification of DNA or RNA
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
87
Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
90
Stable introduction of foreign DNA into chromosome
Applicants:
주식회사 길로 GILO INC. [KR/KR]; 서울시 서초구 효령로 231, 3층 3F, 231, Hyoryeong-ro Seocho-gu, Seoul 06671, KR
Inventors:
김성진 KIM, Seong Jin; KR
정한성 JUNG, Han Sung; KR
다카하시사토루 TAKAHASHI, Satoru; JP
Agent:
리앤목 특허법인 Y.P.LEE, MOCK & PARTNERS; 서울시 강남구 언주로 30길 13 대림아크로텔 12층 12F Daelim Acrotel, 13 Eonju-ro 30-gil Gangnam-gu, Seoul 06292, KR
Priority Data:
10-2017-002960708.03.2017KR
10-2018-002711107.03.2018KR
Title (EN) EXTRACELLULAR MATRIX-PRODUCING COMPOSITION USING MAST4 GENE AND PREPARATION METHOD THEREFOR
(FR) COMPOSITION PRODUCTRICE DE MATRICE EXTRACELLULAIRE UTILISANT LE GÈNE MAST4 ET SON PROCÉDÉ DE PRÉPARATION
(KO) MAST4 유전자를 이용한 세포외 기질 생산용 조성물 및 그 제조방법
Abstract:
(EN) The present invention relates to a composition for producing an extracellular matrix from a eukaryotic cell, the composition comprising a polypeptide or compound capable of specifically binding to a microtubule associated serine/threonine kinase family member 4 (MAST4) protein or a fragment thereof or a polynucleotide, polypeptide or compound capable of specifically binding to a nucleic acid coding for the MAST4 protein or a fragment thereof, and a composition for promoting cartilage regeneration, comprising the same composition.
(FR) La présente invention concerne une composition permettant de produire une matrice extracellulaire à partir d'une cellule eucaryote, la composition comprenant un polypeptide ou un composé capable de se lier spécifiquement à une protéine de la famille 4 des sérine/thréonine kinases associée à des microtubules (MAST4) ou à un fragment de celle-ci ou un polynucléotide, polypeptide ou composé capable de se lier spécifiquement à un acide nucléique codant pour la protéine MAST4 ou à un fragment de celle-ci, et une composition permettant de favoriser la régénération des cartilages, comprenant ladite composition.
(KO) 본 발명은 MAST4(Microtubule Associated Serine/Threonine Kinase Family Member 4) 단백질 또는 이의 단편에 특이적으로 결합할 수 있는 폴리펩티드 또는 화합물, 또는 상기 MAST4 단백질 또는 이의 단편을 코딩하는 핵산에 특이적으로 결합할 수 있는 폴리뉴클레오티드, 폴리펩티드 또는 화합물을 포함하는, 진핵세포로부터 세포외 기질(extracellular matrix)을 생산하기 위한 조성물 및 상기 조성물을 포함하는 연골재생 촉진용 조성물에 관한 것이다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)