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1. (WO2018164385) COMPOSITION FOR DIAGNOSING SJÖGREN'S SYNDROME
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Pub. No.: WO/2018/164385 International Application No.: PCT/KR2018/001815
Publication Date: 13.09.2018 International Filing Date: 12.02.2018
IPC:
C12Q 1/6883 (2018.01) ,G01N 33/68 (2006.01)
[IPC code unknown for C12Q 1/6883]
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants:
가톨릭대학교 산학협력단 THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION [KR/KR]; 서울시 서초구 반포대로 222 222, Banpo-daero Seocho-gu Seoul 06591, KR
Inventors:
정소향 CHUNG, So-Hyang; KR
이현정 LEE, Hyun-Jung; KR
Agent:
위병갑 WIE, Byoung-Gap; KR
Priority Data:
10-2017-002878307.03.2017KR
10-2018-001609009.02.2018KR
Title (EN) COMPOSITION FOR DIAGNOSING SJÖGREN'S SYNDROME
(FR) COMPOSITION PERMETTANT DE DIAGNOSTIQUER LE SYNDROME DE SJÖGREN
(KO) 쇼그렌 증후군 진단을 위한 조성물
Abstract:
(EN) Provided in the present invention are a diagnostic composition for differentiating dry eye from dry eye caused by Sjögren's syndrome by using ATG5 and LC3B-II as biomarkers, a diagnostic method, and a screening method thereof. It is ascertained that when ATG5 and LC3B-II are used as biomarkers, only Sjögren's syndrome, excluding non-Sjögren's syndrome, can be effectively differentiated from dry eye, and thus the present invention can be usable in related industries.
(FR) La présente invention concerne : une composition permettant de différencier un œil sec d'un œil sec provoqué par le syndrome de Sjögren (SS) en utilisant ATG5 et LC3B-II en tant que biomarqueurs; un procédé permettant de diagnostiquer le syndrome de Sjögren; et un procédé permettant de cribler la composition. Selon l'invention, lorsque ATG5 et LC3B-II sont utilisés en tant que biomarqueurs, seul le syndrome de Sjögren, à l'exclusion d'un syndrome autre que le syndrome de Sjögren, peut être efficacement différencié d'un œil sec, et ainsi la présente invention peut être utilisable dans des industries apparentées.
(KO) 본 발명은 ATG5와 LC3B-II를 바이오마커로 이용하는 건성안에서 쇼그렌 증후군 건성안 진단용 조성물, 이의 진단 방법 및 스크리닝 방법을 제공한다. 상기 ATG5와 LC3B-II를 바이오마커로 이용 시, 건성안에서 비-쇼그렌 증후군을 제외한 쇼그렌 증후군만을 효과적으로 진단할 수 있음을 확인하여, 관련 산업에 유용하게 이용될 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)