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1. (WO2018164191) SUBSTITUTED PYRROLIDINE COMPOUND AND USE THEREOF

Pub. No.:    WO/2018/164191    International Application No.:    PCT/JP2018/008811
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Thu Mar 08 00:59:59 CET 2018
IPC: C07D 207/12
A61K 31/4025
A61K 31/4035
A61K 31/404
A61K 31/407
A61K 31/42
A61K 31/427
A61K 31/437
A61K 31/4439
A61K 31/444
A61K 31/454
A61K 31/497
A61K 31/4985
A61K 31/506
A61K 31/5377
A61K 31/5386
A61K 31/55
A61K 31/553
A61P 25/26
A61P 43/00
C07D 207/48
C07D 401/12
C07D 401/14
C07D 403/12
C07D 403/14
C07D 405/12
C07D 405/14
C07D 413/12
C07D 417/14
C07D 471/04
C07D 487/04
C07D 487/10
C07D 491/107
C07D 493/08
C07D 498/08
C07D 498/10
Applicants: TAKEDA PHARMACEUTICAL COMPANY LIMITED
武田薬品工業株式会社
Inventors: DAINI, Masaki
大仁 將揮
MIYANOHANA, Yuhei
宮野鼻 悠平
MIKAMI, Satoshi
味上 達
KAJITA, Yuichi
梶田 雄一
OGINO, Masaki
荻野 正樹
KOIKE, Tatsuki
小池 竜樹
TAKEUCHI, Kohei
竹内 公平
Title: SUBSTITUTED PYRROLIDINE COMPOUND AND USE THEREOF
Abstract:
The present invention provides a substituted pyrrolidine compound having orexin receptor type 2 agonist activity. A compound represented by the formula (in the formula, each symbol is as described in the specification) or a salt thereof has orexin receptor type 2 agonist activity and is useful as an agent for the prevention or treatment of narcolepsy.