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1. (WO2018164141) LYPD1 INHIBITOR AND METHOD FOR PRODUCING BIOLOGICAL TISSUE USING SAME

Pub. No.:    WO/2018/164141    International Application No.:    PCT/JP2018/008630
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Wed Mar 07 00:59:59 CET 2018
IPC: A61K 45/00
A61K 31/713
A61K 38/18
A61K 38/48
A61K 39/395
A61K 48/00
A61P 9/00
Applicants: TOKYO WOMEN'S MEDICAL UNIVERSITY
学校法人東京女子医科大学
Inventors: MATSUURA, Katsuhisa
松浦 勝久
SHIMIZU, Tatsuya
清水 達也
AOKI, Shinako
青木 信奈子
SAKAMOTO, Satoru
阪本 覚
Title: LYPD1 INHIBITOR AND METHOD FOR PRODUCING BIOLOGICAL TISSUE USING SAME
Abstract:
Provided is a LYPD1 inhibitor for promoting vascular endothelial network formation in a biological tissue. Also provided is a medicinal composition, said medicinal composition comprising a LYPD1 inhibitor as an active ingredient, for treating and/or preventing neoangiogenic disorders. Also provided is a method which comprises: (a1) a step for providing a cell population containing first cells expressing LYPD1 and vascular endothelial cells; (a2) a step for treating the cell population obtained in step (a1) with a LYPD1 inhibitor; and (a3) a step for culturing the cell population obtained in step (a2).