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1. (WO2018164098) CELL POPULATION TO BE USED AS HEART FIBERIZATION MODEL, METHOD FOR PRODUCING SAME, SCREENING METHOD USING SAME, METHOD FOR EVALUATING HEART FIBERIZATION MODEL USING SAME, AND SYSTEM FOR EVALUATING HEART FIBERIZATION MODEL
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Pub. No.: WO/2018/164098 International Application No.: PCT/JP2018/008511
Publication Date: 13.09.2018 International Filing Date: 06.03.2018
IPC:
C12N 5/077 (2010.01) ,C12M 3/00 (2006.01) ,C12N 5/0735 (2010.01) ,C12N 5/10 (2006.01) ,G01N 33/15 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
077
Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3
Tissue, human, animal or plant cell, or virus culture apparatus
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
073
Embryonic cells or tissues; Foetal cells or tissues
0735
Embryonic stem cells; Embryonic germ cells
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
10
Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
15
Medicinal preparations
Applicants:
国立大学法人大阪大学 OSAKA UNIVERSITY [JP/JP]; 大阪府吹田市山田丘1番1号 1-1, Yamadaoka, Suita-shi, Osaka 5650871, JP
株式会社カルディオ CARDIO INCORPORATED [JP/JP]; JP
Inventors:
澤 芳樹 SAWA, Yoshiki; JP
宮川 繁 MIYAGAWA, Shigeru; JP
齋藤 充弘 SAITO, Atsuhiro; JP
伊勢岡 弘子 ISEOKA, Hiroko; JP
柳 裕啓 YANAGI, Yasuhiro; JP
Agent:
特許業務法人三枝国際特許事務所 SAEGUSA & PARTNERS; 大阪府大阪市中央区道修町1-7-1 北浜TNKビル Kitahama TNK Building, 1-7-1, Doshomachi, Chuo-ku, Osaka-shi, Osaka 5410045, JP
Priority Data:
2017-04193006.03.2017JP
2017-05139416.03.2017JP
Title (EN) CELL POPULATION TO BE USED AS HEART FIBERIZATION MODEL, METHOD FOR PRODUCING SAME, SCREENING METHOD USING SAME, METHOD FOR EVALUATING HEART FIBERIZATION MODEL USING SAME, AND SYSTEM FOR EVALUATING HEART FIBERIZATION MODEL
(FR) POPULATION DE CELLULES À UTILISER EN TANT QUE MODÈLE DE FIBRAGE DE CŒUR, PROCÉDÉ POUR SA PRODUCTION, PROCÉDÉ DE CRIBLAGE L'UTILISANT, PROCÉDÉ D'ÉVALUATION DE MODÈLE DE FIBRAGE DE CŒUR L'UTILISANT ET SYSTÈME D'ÉVALUATION DE MODÈLE DE FIBRAGE DE CŒUR
(JA) 心臓線維化モデルとして用いられる細胞集団、その製造方法、それを利用したスクリーニング方法及び心臓線維化モデルの評価方法、並びに心臓線維化モデルの評価システム
Abstract:
(EN) Provided is a heart fiberization model which is more closely similar to a myocardial tissue. A cell population which can be obtained by culturing a cell population containing pluripotent stem cell-derived cardiomyocytes in the presence of a fiberization inducer.
(FR) L'invention porte sur un modèle de fibrage du cœur qui est plus étroitement similaire à un tissu myocardique. L'invention concerne une population de cellules qui peut être obtenue par culture d'une population de cellules contenant des cardiomyocytes dérivés de cellules souches pluripotentes en présence d'un inducteur de fibrage.
(JA) 心筋組織により近い、心臓線維化モデルを提供する。 多能性幹細胞由来心筋細胞を含む細胞集団を線維化誘導因子の存在下で培養することにより得られうる、細胞集団。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)