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1. (WO2018163926) TANDEM MASS SPECTROMETRY DEVICE AND PROGRAM FOR SAME DEVICE

Pub. No.:    WO/2018/163926    International Application No.:    PCT/JP2018/007423
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Thu Mar 01 00:59:59 CET 2018
IPC: H01J 49/40
G01N 27/62
Applicants: SHIMADZU CORPORATION
株式会社島津製作所
Inventors: TOYAMA, Atsuhiko
遠山 敦彦
YAMAMOTO, Hideki
山本 英樹
Title: TANDEM MASS SPECTROMETRY DEVICE AND PROGRAM FOR SAME DEVICE
Abstract:
In this invention, when data is obtained by mass spectrometry, a mass spectrum analysis unit (32) immediately determines the integration value of signal intensities on the mass spectrum for each m/z sub-range of a predetermined m/z-width into which the entire m/z range for the substance being measured is divided. Then, the mass spectrum analysis unit (32) selects only the m/z sub-ranges which have signal intensity integration values equal to or greater than a predetermined threshold value for MS/MS analysis. For each of the m/z sub-ranges selected, the MS/MS analysis is executed by an MS/MS analysis control unit (41), taking as a precursor ion an ion whereof the m/z is included within the m/z sub-range. After executing repeatedly a measurement cycle containing one iteration of mass spectrometry and one or a plurality of iterations of MS/MS analysis in this manner, an identification processing unit (35) sorts out the ions derived from an identical component on the basis of the peak retention times in an extracted-ion chromatogram of each product ion, and identifies the component. In this manner, while collecting information on a product ion derived from an ion observed in the mass spectrum as thoroughly as possible, the number of MS/MS analyses executed can be reduced, thereby shortening the time for one measurement cycle.