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1. (WO2018162785) COMPOUNDS FOR THE TREATMENT OF DISEASES CAUSED BY OXALATE ACCUMULATION

Pub. No.:    WO/2018/162785    International Application No.:    PCT/ES2018/070184
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Tue Mar 13 00:59:59 CET 2018
IPC: A61K 31/625
A61P 13/04
Applicants: UNIVERSIDAD DE GRANADA
UNIVERSIDAD DE LA LAGUNA
Inventors: DÍAZ GAVILÁN, Mónica
GÓMEZ VIDAL, José Antonio
MOYA GARZÓN, María Dolores
SALIDO RUIZ, Eduardo
MARTÍN HIGUERAS, Cristina
FERNANDES, Miguel Xavier
Title: COMPOUNDS FOR THE TREATMENT OF DISEASES CAUSED BY OXALATE ACCUMULATION
Abstract:
The present invention relates to the use of derivatives of salicylic acid for the treatment of diseases or conditions linked to GO and/or PRODH2 enzyme activity, in particular diseases linked to an excess of oxalate, and for the treatment of patients with renal insufficiency (uremia or azotaemia) receiving haemodialysis or peritoneal dialysis, in particular patients treated with ascorbic acid (vitamin C), which is metabolised to oxalate, or patients with fibromyalgia and vulvar pain.