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1. (WO2018162754) PREPARING AND USE OF GLU-PLASMINOGEN FROM BLOOD FRACTIONS

Pub. No.:    WO/2018/162754    International Application No.:    PCT/EP2018/055984
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Sat Mar 10 00:59:59 CET 2018
IPC: C12N 9/68
C07K 1/18
A61K 38/48
Applicants: PREVIPHARMA CONSULTING GMBH
Inventors: GRUBER, Ricarda
GERDING, Hanne Rieke
MAZUR, Marc
KIESSIG, Stephan T.
KARGES, Hermann E.
Title: PREPARING AND USE OF GLU-PLASMINOGEN FROM BLOOD FRACTIONS
Abstract:
The present invention relates to a method for isolating Glu-plasminogen, said method comprising the anion exchange chromatography of blood plasma or a plasma fraction comprising Glu-plasminogen. Furthermore, the present invention relates to Glu-plasminogen obtainable from the method of the present invention and its use in a method for treating a patient suffering from or being at risk of developing a disorder selected from the group consisting of organ failure, a thrombotic event, arterial obstructive disease, microcirculation, disseminated intravascular coagulation (DIC), and a combination of two or more thereof.