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1. (WO2018162727) PHARMACEUTICAL COMBINATIONS COMPRISING AN ANTI-LY75 ANTIBODY

Pub. No.:    WO/2018/162727    International Application No.:    PCT/EP2018/055939
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Sat Mar 10 00:59:59 CET 2018
IPC: C07K 16/28
A61P 35/00
A61P 35/02
A61K 39/395
A61K 47/68
A61K 31/505
C07K 16/46
Applicants: BERLIN-CHEMIE AG
Inventors: BINASCHI, Monica
BIGIONI, Mario
MERLINO, Giuseppe
SIMONELLI, Cecilia
BERTONI, Francesco
PELLACANI, Andrea
Title: PHARMACEUTICAL COMBINATIONS COMPRISING AN ANTI-LY75 ANTIBODY
Abstract:
The present disclosure relates generally to the fields of immunology and molecular biology. More specifically, provided herein are pharmaceutical combinations comprising (A) antibodies, or antigen-binding portions thereof, directed against LY75, and (B) a second anti-cancer entity; nucleic acids encoding antibody combinations; methods for preparing antibody combinations; and methods for the treatment of diseases, such as cancers mediated by LY75 expression or activity.