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1. (WO2018162676) DISINTEGRATABLE POROUS ORGANOSILICA OR ORGANOMETALOXIDE NANOPARTICLES AND USES THEREOF AS VEHICLE FOR CONTROLLED DELIVERY OF siRNA

Pub. No.:    WO/2018/162676    International Application No.:    PCT/EP2018/055829
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Fri Mar 09 00:59:59 CET 2018
IPC: A61K 9/51
Applicants: UNIVERSITÉ DE STRASBOURG
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
IHU STRASBOURG - INSTITUT HOSPITALO-UNIVERSITAIRE DE STRASBOURG
INSERM - INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE -
Inventors: DE COLA, Luisa
BAUMERT, Thomas
MAGGINI, Laura
GIGLIO, Valentina
DENTINGER, Mike
Title: DISINTEGRATABLE POROUS ORGANOSILICA OR ORGANOMETALOXIDE NANOPARTICLES AND USES THEREOF AS VEHICLE FOR CONTROLLED DELIVERY OF siRNA
Abstract:
The present invention relates to disintegratable porous organometaloxide (e.g., organosilica) nanoparticles for the delivery of nucleic acid-type biomolecules such as siRNA, a method for producing the same, and uses thereof including their use for prevention and treatment of human cancer.