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1. (WO2018162368) USE OF COMPATIBLE SOLUTES

Pub. No.:    WO/2018/162368    International Application No.:    PCT/EP2018/055251
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Tue Mar 06 00:59:59 CET 2018
IPC: A61K 8/36
A61K 8/49
A61Q 19/02
Applicants: MERCK PATENT GMBH
Inventors: HEIDER, Lilia
HAMASAKI, Takeshi
MASAKI, Hitoshi
Title: USE OF COMPATIBLE SOLUTES
Abstract:
The present invention relates tothe use of at least one compatible solute and/or its physiologically acceptable salt for countering age-related skin color change or for the suppression and/or reduction of protein carbonylationand/or for the suppression and/or reduction of the accumulation of carbonylated proteins in the stratum corneum. The invention is further directed to formulations comprising at least one compatible solute and/or its physiologically acceptable salt and at least one further skin pore lightening active, as well as a process for preparing such formulation.