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1. (WO2018162346) CULTURE MEDIUM COMPRISING OLIGOPEPTIDES

Pub. No.:    WO/2018/162346    International Application No.:    PCT/EP2018/055179
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Sat Mar 03 00:59:59 CET 2018
IPC: C12N 5/00
Applicants: EVONIK TECHNOCHEMIE GMBH
Inventors: KNAUP, Günter
MERZ, Friedhelm
KESSLER, Christian
Title: CULTURE MEDIUM COMPRISING OLIGOPEPTIDES
Abstract:
The invention relates to a culture medium, preferably a cell culture medium, comprising at least one oligopeptide of 2-10 amino acids in length, said amino acids being natural amino acids and at least one of said amino acids being lysine (Lys) and one further amino acid is selected from cysteine (Cys), cystine (Cyss), leucine (Leu), tyrosine (Tyr), valine (Val) and Isoleucine (Ile) and the oligopeptide is present in an amount of at least 0.1 mM. The invention further relates to the use of a culture medium of the invention for culturing cells, preferably plant cells, animal cells or mammalian cells. Another aspect of the invention relates to a method of manufacturing a cell culture product comprising the steps of (i) providing a cell capable of producing said cell culture product; (ii) contacting said cell with a culture medium according to the invention; and (iii) obtaining said cell culture product from said culture medium or from said cell.