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1. (WO2018162307) SEIZURE CHARACTERIZATION WITH MAGNETIC RESONANCE IMAGING (MRI) FUSED WITH AN ELECTROENCEPHALOGRAPHY (EEG) MODEL

Pub. No.:    WO/2018/162307    International Application No.:    PCT/EP2018/055004
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Fri Mar 02 00:59:59 CET 2018
IPC: A61B 5/00
A61B 5/0476
A61B 5/055
G16H 50/20
Applicants: KONINKLIJKE PHILIPS N.V.
PHOENIX CHILDREN'S HOSPITAL
Inventors: ZAGORCHEV, Lyubomir, Georgiev
WENZEL, Fabian
MEYER, Carsten
BERGTHOLDT, Martin
HU, Houchun
MILLER, Jeffrey
Title: SEIZURE CHARACTERIZATION WITH MAGNETIC RESONANCE IMAGING (MRI) FUSED WITH AN ELECTROENCEPHALOGRAPHY (EEG) MODEL
Abstract:
A seizure characterization method includes correlating locations of electrodes placed around a brain and used to produce sequential electroencephalography (EEG) signals with a three-dimensional anatomical brain model derived from magnetic resonance imaging (MRI). The sequential EEG signals are modelled from the electrodes placed around the brain in three dimensions using cortical and sub-cortical brain regions included in the brain model to define constraints for the numerical solution. Amounts of the sequential EEG signals are quantified in three dimensions relative to the brain regions included in the brain model. The method also includes establishing, based on the quantifying, at least one propagation pattern of the sequential EEG signals in time relative to the brain regions in the brain model.