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1. (WO2018162277) ENHANCED SAMPLING USING APPLIED ENERGY

Pub. No.:    WO/2018/162277    International Application No.:    PCT/EP2018/054743
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Wed Feb 28 00:59:59 CET 2018
IPC: A61B 5/15
A61B 5/157
A61B 5/145
A61B 10/00
A61B 5/155
Applicants: KONINKLIJKE PHILIPS N.V.
Inventors: GERHARDT, Lutz, Christian
JOHNSON, Mark, Thomas
UZUNBAJAKAVA, Natallia, Eduardauna
WORTELBOER, Pippinus, Maarten, Robertus
GROB, Timon, Rutger
STAPERT, Hendrik, Roelof
Title: ENHANCED SAMPLING USING APPLIED ENERGY
Abstract:
The present disclosure is directed to enhanced sampling of bioanalytes from bodily fluids using wearable and/or insertable devices. In some embodiments, an apparatus (100, 500, 600) for sampling bioanalyte(s) in tissue (107, 507, 607) may include: a base (102, 502, 602) having conduit(s) adapted to receive fluid extracted from the tissue; microneedles (106, 306, 506, 606) fluidly coupled with the conduit(s) and adapted to be pierced into the tissue; a plurality of individually-controllable energy emitters (112, 114, 350, 612, 614); and logic (90) operably coupled with the plurality of individually-controllable energy-emitters. The logic may be adapted to operate a subset of the plurality of individually-controllable energy emitters to apply energy at a first subset of the microneedles to induce bioanalyte flow through tissue towards the first subset or a second subset of the microneedles, or through the first subset or a second subset of the microneedles.