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1. (WO2018161417) METHOD FOR CONSTRUCTING HUMANIZED MOUSE MODEL FOR CHRONIC HEPATITIS B BY USING STEM CELLS

Pub. No.:    WO/2018/161417    International Application No.:    PCT/CN2017/081750
Publication Date: Fri Sep 14 01:59:59 CEST 2018 International Filing Date: Tue Apr 25 01:59:59 CEST 2017
IPC: C12N 5/071
A01K 67/027
Applicants: ZHEJIANG UNIVERSITY
浙江大学
Inventors: LI, Jun
李君
LI, Jiang
李江
SUN, Suwan
孙苏婉
LI, Lanjuan
李兰娟
Title: METHOD FOR CONSTRUCTING HUMANIZED MOUSE MODEL FOR CHRONIC HEPATITIS B BY USING STEM CELLS
Abstract:
Provided is a method for constructing a humanized mouse model for chronic hepatitis B by using stem cells. The method comprises obtaining human stem cells, transplanting the stem cells into a mouse with liver damage, infecting a humanized mouse with HBV, and like steps.