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1. (WO2018160897) PREVENTING POST-ICTAL HEADACHES
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Pub. No.: WO/2018/160897 International Application No.: PCT/US2018/020537
Publication Date: 07.09.2018 International Filing Date: 01.03.2018
IPC:
A61K 39/395 (2006.01) ,C07K 16/18 (2006.01) ,A61P 25/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
06
Antimigraine agents
Applicants:
BETH ISRAEL DEACONESS MEDICAL CENTER, INC. [US/US]; 330 Brookline Avenue Boston, Massachusetts 02215, US
Inventors:
BURSTEIN, Rami; US
Agent:
GARCIA, Todd E.; US
Priority Data:
62/466,15802.03.2017US
62/490,95327.04.2017US
62/514,34602.06.2017US
62/516,40607.06.2017US
Title (EN) PREVENTING POST-ICTAL HEADACHES
(FR) PRÉVENTION DE CÉPHATÉE POST-ICTALE
Abstract:
(EN) Disclosed herein are methods of preventing incidence of a migrainous or non migrainous post-ictal headache, and/or at least one secondary symptom associated with a migrainous post-ictal headache in a subject comprising administering to the subject a monoclonal antibody that modulates the CGRP pathway. Compositions for use in the disclosed methods are also provided.
(FR) L'invention concerne des méthodes de prévention de l'incidence d'une céphalée post-ictale migraineuse ou non migraineuse, et/ou d'au moins un symptôme secondaire associé à une céphalée post-ictale migraineuse chez un sujet, comprenant l’administration au sujet d’un anticorps monoclonal qui assure la modulation de la voie du CGRP. L'invention concerne également des compositions destinées à être utilisées dans les méthodes de l'invention.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)