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|1. (WO2018160675) METHODS FOR DIAGNOSING, PROGNOSING, AND TREATING COLORECTAL CANCER USING BIOMARKER EXPRESSION|
|Applicants:||BAYLOR RESEARCH INSTITUTE
|Title:||METHODS FOR DIAGNOSING, PROGNOSING, AND TREATING COLORECTAL CANCER USING BIOMARKER EXPRESSION|
Dysregulated expression of microRNAs (miRNAs) has emerged as a hallmark feature in human cancers. Aspects of the disclosure relate to methods for selecting optimal therapy for a patient from several alternative treatment options. A major clinical challenge in cancer treatment is to identify the subset of patients who will benefit from a therapeutic regimen, both in metastatic and adjuvant settings. The number of anti-cancer drugs and multi-drug combinations has increased substantially in the past decade, however, treatments continue to be applied empirically using a trial-and-error approach. Here methods and compositions are provided to determine the optimal treatment option for cancer patients.