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1. (WO2018160644) NANOBEAD CONTAINING BIOSENSORS AND METHODS OF PRODUCTION AND USE THEREOF

Pub. No.:    WO/2018/160644    International Application No.:    PCT/US2018/020136
Publication Date: Sat Sep 08 01:59:59 CEST 2018 International Filing Date: Thu Mar 01 00:59:59 CET 2018
IPC: C12Q 1/58
G01N 27/327
Applicants: SIEMENS HEALTHCARE DIAGNOSTICS INC.
Inventors: WILSON, Michael S.
Title: NANOBEAD CONTAINING BIOSENSORS AND METHODS OF PRODUCTION AND USE THEREOF
Abstract:
Multi-use biosensors are disclosed that include enzymes coupled to nanobeads; the multi-use biosensors are used to detect analytes in fluidic biological samples, and the biosensors also maintain their enzyme activity after many uses. Multi-sensor arrays are disclosed that include multiple biosensors. Also disclosed are methods of producing and using these devices.