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1. (WO2018160622) COMPOSITIONS AND METHODS FOR CAR T CELL THERAPY

Pub. No.:    WO/2018/160622    International Application No.:    PCT/US2018/020095
Publication Date: Sat Sep 08 01:59:59 CEST 2018 International Filing Date: Thu Mar 01 00:59:59 CET 2018
IPC: A61K 35/17
C07K 14/725
C07K 14/705
C07K 16/28
Applicants: ENDOCYTE, INC.
PURDUE RESEARCH FOUNDATION
Inventors: LOW, Philip Stewart
CHU, Haiyan
LEE, Yong Gu
LU, Yingjuan J.
LEAMON, Christopher Paul
WHEELER II, Leroy W.
Title: COMPOSITIONS AND METHODS FOR CAR T CELL THERAPY
Abstract:
The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.