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1. (WO2018160574) MICROFLUIDIC DEVICES AND RELATED METHODS
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Pub. No.: WO/2018/160574 International Application No.: PCT/US2018/019975
Publication Date: 07.09.2018 International Filing Date: 27.02.2018
IPC:
B01L 3/00 (2006.01) ,C12Q 1/00 (2006.01) ,C12Q 1/68 (2018.01) ,C12Q 1/6806 (2018.01) ,G01N 33/48 (2006.01)
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
L
CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3
Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
[IPC code unknown for C12Q 1/6806]
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
Applicants:
ARMES, Niall A. [GB/GB]; GB
PIEPENBURG, Olaf [GB/GB]; GB
GREENWOOD, Catherine Jean [GB/GB]; GB
NENTWICH, Oliver [GB/GB]; GB
ALERE SAN DIEGO INC. [US/US]; 9975 Summers Ridge Road San Diego, California 92121, US
Inventors:
ARMES, Niall A.; GB
PIEPENBURG, Olaf; GB
GREENWOOD, Catherine Jean; GB
NENTWICH, Oliver; GB
ZU SCHWEINSBERG, Alexander Schenk; US
DERFUS, Austin Matthew; US
DAVIDSON, Justin; US
KUMARAVADIVELU, Karthikeyan; US
PATEL, Maulik Vinod; US
Agent:
ARENSON, Tanya A.; US
Priority Data:
62/464,57628.02.2017US
Title (EN) MICROFLUIDIC DEVICES AND RELATED METHODS
(FR) DISPOSITIFS MICROFLUIDIQUES ET PROCÉDÉS ASSOCIÉS
Abstract:
(EN) A microfluidic device includes an inlet port configured to receive a sample, a first reaction chamber fluidically coupled to the inlet port, a first pump fluidically coupled to the inlet port, a second pump fluidically coupled to a mixing chamber, a metering channel fluidically coupled to the first reaction chamber and to the mixing chamber, and one or more second reaction chambers fluidically coupled to the mixing chamber. The first pump is configured to move fluid from the inlet port to the first reaction chamber and from the first pump to the inlet port. The second pump is configured to move fluid from the second pump to the mixing chamber, from the first reaction chamber to the mixing chamber, and from the mixing chamber to the one or more second reaction chambers.
(FR) Un dispositif microfluidique comprend un orifice d'entrée configuré pour recevoir un échantillon, une première chambre de réaction couplée fluidiquement à l'orifice d'entrée, une première pompe couplée fluidiquement à l'orifice d'entrée, une seconde pompe couplée fluidiquement à une chambre de mélange, un canal de dosage couplé fluidiquement à la première chambre de réaction et à la chambre de mélange, et une ou plusieurs secondes chambres de réaction couplées de manière fluidique à la chambre de mélange. La première pompe est configurée pour déplacer le fluide à partir de l'orifice d'entrée à la première chambre de réaction et à partir de la première pompe à l'orifice d'entrée. La seconde pompe est configurée pour déplacer le fluide à partir de la seconde pompe à la chambre de mélange, à partir de la première chambre de réaction à la chambre de mélange, et à partir de la chambre de mélange à la ou aux secondes chambres de réaction.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)