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1. (WO2018160553) IMPROVED KITS AND ASSAYS TO DETECT CIRCULATING MULTIPLE MYELOMA CELLS FROM BLOOD
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Pub. No.: WO/2018/160553 International Application No.: PCT/US2018/019925
Publication Date: 07.09.2018 International Filing Date: 27.02.2018
IPC:
G01N 33/50 (2006.01) ,G01N 33/574 (2006.01) ,C12N 15/13 (2006.01) ,A61K 51/10 (2006.01) ,A61K 39/44 (2006.01) ,B03C 1/005 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
574
for cancer
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
12
Genes encoding animal proteins
13
Immunoglobulins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
02
characterised by the carrier
04
Organic compounds
08
Peptides, e.g. proteins
10
Antibodies or immunoglobulins; Fragments thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
44
Antibodies bound to carriers
[IPC code unknown for B03C 1/05]
Applicants:
MENARINI SILICON BIOSYSTEMS, INC. [US/US]; 10355 Science Center Dr. #210 San Diego, California 92121, US
Inventors:
FOULK, Brad; US
RAO, Galla Chandra; US
GROSS, Steven; US
MORANO, Carrie Capps; US
Agent:
SCHORR, Kristel; US
AGARWAL, Pavan K.; US
BECK, George; US
BERKOWITZ, Benjamin; US
BRINCKERHOFF, Courtenay; US
FELDHAUS, John J.; US
KAMINSKI, Michael D.; US
LAW, Glenn; US
MAEBIUS, Stephen; US
QUILLIN, George E.; US
RAWLINS, Andrew E.; US
SIMKIN, Michele; US
Priority Data:
62/464,58528.02.2017US
Title (EN) IMPROVED KITS AND ASSAYS TO DETECT CIRCULATING MULTIPLE MYELOMA CELLS FROM BLOOD
(FR) KITS ET DOSAGES AMÉLIORÉS POUR DÉTECTER DES CELLULES DE MYÉLOME MULTIPLE CIRCULANTES À PARTIR DU SANG
Abstract:
(EN) Disclosed herein are reagents, compositions and methods for isolating and detecting rare cells such as circulating multiple myeloma cells as well as method of evaluating and treating patients suspected of having diseases of abnormal plasma cells, such as multiple myeloma.
(FR) La présente invention concerne des réactifs, des compositions et des procédés pour isoler et détecter des cellules rares, telles que des cellules de myélome multiple circulantes, ainsi que des procédés d'évaluation et de traitement de patients suspectés de souffrir de maladies de cellules plasmatiques anormales, telles que le myélome multiple.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)