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1. (WO2018160534) PROTECTION OF BETA CELLS FROM IMMUNE ATTACK

Pub. No.:    WO/2018/160534    International Application No.:    PCT/US2018/019862
Publication Date: Sat Sep 08 01:59:59 CEST 2018 International Filing Date: Wed Feb 28 00:59:59 CET 2018
IPC: A61K 38/28
A61K 48/00
C12N 5/22
Applicants: JOSLIN DIABETES CENTER
Inventors: KISSLER, Stephan
YI, Peng
Title: PROTECTION OF BETA CELLS FROM IMMUNE ATTACK
Abstract:
Compositions of genetically modified beta-like cells are encompassed. Also encompassed are methods of treatment of type 1 diabetes using these compositions or compositions that inhibit the function of the identified genes.