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1. (WO2018160091) CYCLOBUTYL (S)-2-[[[(R)-2-(6-AMINOPURIN-9-YL)-1-METHYL-ETHOXY]METHYL-PHENOXY-PHOSPHORYL]AMINO]-PROPANOATES, AND METHOD FOR PRODUCING AND USING SAME

Pub. No.:    WO/2018/160091    International Application No.:    PCT/RU2017/000212
Publication Date: Sat Sep 08 01:59:59 CEST 2018 International Filing Date: Sat Apr 08 01:59:59 CEST 2017
IPC: C07F 9/656
C07F 9/44
C07C 57/15
C07C 53/16
A61K 31/664
A61K 31/675
A61P 31/18
Applicants: IVACHTCHENKO, Alexandrе Vasilievich
ИВАЩЕНКО, Александр Васильевич
IVASHCHENKO, Andrey Alexandrovich
ИВАЩЕНКО, Андрей Александрович
IVACHTCHENKO, Alena Alexandrovna
ИВАЩЕНКО, Алена Александровна
SAVCHUK, Nikolay Filippovich
САВЧУК, Николай Филиппович
ALLA CHEM LLC
АЛЛА ХЕМ ЛЛС
Inventors: IVACHTCHENKO, Alexandrе Vasilievich
ИВАЩЕНКО, Александр Васильевич
MITKIN, Oleg Dmitrievich
МИТЬКИН, Олег Дмитриевич
Title: CYCLOBUTYL (S)-2-[[[(R)-2-(6-AMINOPURIN-9-YL)-1-METHYL-ETHOXY]METHYL-PHENOXY-PHOSPHORYL]AMINO]-PROPANOATES, AND METHOD FOR PRODUCING AND USING SAME
Abstract:
The present invention relates to chemotherapeutic agents for treating viral and cancerous diseases. The present compounds are prodrugs of human immunodeficiency virus (HIV) and hepatitis B virus (HBV) DNA polymerase inhibitors, and are intended for treating the human immunodeficiency virus, hepatitis B, and co-infections of HIV/HCV, HIV/HBV, HIV/HCV/HBV and HCV/HBV.